Hey guys! I'm a current MS patient that is having a lot of problems at the moment. Im on my third type of treatment and it is not working well at all.  I started out on Rebiff which was a nightmare. I then switched to Tysabri and just when it started to help me feel better, I had to come off of it because my chances for PML was rising. It also caused me to contract extreme RA in my hands! I cant remember the name of the medicine that Im on now but its supposed to be treating the MS and RA all together. Im still having to take steroids for my hands, although I have been able to lower the dosage some. But I feel like total hell! Im wondering if there are any other MS patients here that can relate and what medications may or may not be working for you?