Researchers have found evidence that two trading bots, named Willie and Markus were responsible for market manipulation on the Mt Gox exchange in 2014. To make matters worse, they claim that these bots traded with Bitcoin they didn't have and sent signals of healthy market growth. 
Price Manipulation in the Bitcoin Ecosystem - https://www.sciencedirect.com/science/article/pii/S0304393217301666 

https://youtu.be/XfJUaXHuNBI

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