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I am starting this contest to increase awareness and appreciation of the most fundamental principles of science among layman. In each contest, I will ask a question based on some fundamental concepts of science which will trigger some scientific discussion. Anyone can answer the question. But for winning this contest, you should contribute more than that. You should actively involve by replying to this post directly or replying to other comments. Winner will be the one who have contributed more by answering, explaining and clearing the doubts and misunderstandings of the other participants. The winner will get the full SBD payment of this post. I am the only judge for this contest. I diserve the right to choose the winner. No objects will be entertained. Since I am the judge I may not participate in your discussion. But I diserve the right to join your discussion sometime, if needed. Once I get the payment for this post, I will announce the winner along with a brief answer and my thoughts on the topic of discussion.

Today's question is,

"What is the fundamental theory of science which can explain the phenomenon of antibiotic resistance ?"

Clue - This theory is not anymore just a theory. It's a fact in modern biology.